Partial opioid agonists bind to opioid receptor sites but don’t generate a full response. In some cases, they may activate one receptor site and suppress another.

Methadone is a full agonist of the mu opioid receptor, meaning that when the drug meets the receptor in the brain, it activates it, causing a biochemical reaction that leads to euphoria and pain ...

“A partial mu-opioid receptor agonist, buprenorphine may insufficiently mitigate opioid cravings and precipitate withdrawal in patients who use fentanyl, which is 50 to 100 times more potent ...

Opioid agonists are substances that activate opioid receptors. They have a variety of uses, from pain management to managing opioid withdrawal symptoms.

The study looked at 120 patient encounters across three emergency rooms in central Missouri.

Mu opioid receptor and PD-1 are co-expressed in pain-sensing sensory neurons. Morphine antinociception is diminished in mice or nonhuman primates by immunotherapy targeting PD-1, whereas PD-L1 ...

Salix Pharmaceuticals has launched the first connected TV commercial for its opioid-induced constipation drug Relistor.