The direct comparison of mice lacking each of the three opioid-receptor genes reveals that mu- and delta-opioid receptors act oppositely in regulating emotional reactivity. This highlights a novel ...

An A118G nucleotide exchange in exon 1 of the mu-opioid receptor causes an Asn40Asp substitution polymorphism in the receptor's extracellular domain. In vitro studies show that the Asp40 variant ...

New findings show that heavy drinkers with the G allele of the A118G polymorphism of the mu-opioid receptor gene have greater cravings after alcohol exposure than heavy drinkers homozygous for the ...

Those attempts were doomed to failure because all opioid drugs interact with the brain in the same way. They dock to a specific neural receptor, the mu-opioid receptor, which controls the effects ...

Since levels of mu, delta, and kappa opiate receptors -- the three main types of opioid receptor in the brain and spinal cord -- are not thought to differ dramatically in men and women ...

They’re the only opioid receptor that doesn’t cause respiratory depression. They can also have an anti-reward, dysphoric effect, which is the opposite effect of mu receptors. So, while they do ...

Professor Anne Roivainen from the Turku PET Centre tells that this is the first time mu-opioid receptor levels have been assessed in peripheral regions using positron emission tomography (PET ...

Your body has three primary opioid receptor types: mu, delta, and kappa. These receptors are found on the surface of cells in the central and peripheral nervous systems. They respond to your body ...

Naloxegol is an antagonist of opioid binding at the mu-opioid receptor. Naloxegol functions as a peripherally acting mu-opioid receptor antagonist in tissues such as the gastrointestinal tract ...

Many of these functions are regulated by the mu-opioid receptor (MOR) system," the authors explain. These findings were published May 30 in the journal Neuropsychopharmacology. "We found that the ...