Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

More information: Atsuho Morita et al, Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells, npj Regenerative Medicine (2025). DOI: 10.1038/s41536-025-00411-4 ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology. The AT2-like ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood cells that defend the body by killing microbes, removing dead cells ...

Credit: Nature Cardiovascular Research (2025). DOI: 10.1038/s44161-025-00681-7 Lymphatic vessels (green) are wrapped around blood vessels (red) in a mouse lung.

These previous experiments led to testing the dextromethorphan in mouse models of lung fibrosis, but also in live 3D organotypic human lung tissue cultured in the lab. “Being part of a ...