Affinity of antibody before and after humanization Before humanization, mouse antibody KD=6.38E-12M. Image Credit: Sino Biological After humanization, humanized antibody KD=3.90E-12M.

A monoclonal antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with F9 teratocarcinoma cells is described. This antibody, which reacts with embryonal carcinoma ...