First, in spite of having “only” moderate to severe mitral regurgitation, these patients with HF were quite advanced, as evidenced by their high baseline natriuretic peptide levels, ...

We conducted a randomized, controlled trial involving patients with heart failure and moderate to severe functional mitral regurgitation from 30 sites in nine countries. The patients were assigned ...

Among patients with moderate or severe TR, 41% had AFTR, while 59% had VFTR. VFTR was more common in patients with severe TR and was linked to more persistent AFib and advanced heart failure symptoms.

In the United States, mitral regurgitation is the most common cause of moderate-to-severe valvular heart disease among adults older than 55 years of age. 2 In a cross-sectional cohort study ...

The same stair step across mild to moderate to severe TR was seen for all-cause mortality at 1 year (adjusted HR 1.17, 95% CI 1.04-1.32 and aHR 1.49, 95% CI 1.29-1.72), with a nonsignificant trend ...

Trans-septal Mitral Valve Replacement with HighLife Valve in a Patient with Moderate-Severe Mitral Regurgitation. Presenter: Thomas E. Waggoner. June 10, 2023. REGISTER for free or LOG IN to view this ...

Mild Residual Mitral Regurgitation With High Gradient Versus Moderate Regurgitation With Low Gradient After Mitral Transcatheter Edge-to-Edge Repair: A Systematic Review and Meta-Analysis. Presenter: ...

Source Reference: Anker SD, et al "Transcatheter valve repair in heart failure with moderate to severe mitral regurgitation" N Engl J Med 2024; DOI: 10.1056/NEJMoa2314328. Secondary Source Journal ...

Mitral transcatheter edge-to-edge repair (M-TEER) reduced cardiovascular death and heart failure (HF)-related hospitalizations with improved health status in patients with HF and moderate to ...

In patients with severe tricuspid regurgitation, transcatheter tricuspid valve replacement plus medical therapy improved outcomes compared with medical therapy alone, researchers reported at TCT 2024.