Mitochondrial dysfunction has long been associated with aging, making preventing or reversing the organelle’s decay a high priority for longevity researchers. One key target for such work is the ...

mitochondrial membrane potential loss, and permeability transition pore activation, which can culminate in cell death. A review by a team of researchers at the Chinese Academy of Science ...

Changes in the relative mitochondrial membrane potential were detected in both yeasts and Jurkat cells. These results indicate that edelfosine induces apoptosis in yeasts in addition to human ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

mitochondrial membrane potential loss, and permeability transition pore activation, which can culminate in cell death. A review by a team of researchers at the Chinese Academy of Science ...

Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...

Additionally, safranin fluorescence assays were conducted further to confirm the elevated membrane potential in the mutant mitochondria and compare it to that of the wild-type and complemented lines.

Elamipretide is a cell-permeable peptide compound designed to improve mitochondrial function by targeting the inner mitochondrial membrane where it binds reversibly ... as quickly as possible ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ ...