Changes in how brain cells generate energy may drive the development of Alzheimer's disease and influence how patients ...

Brain Signals May Predict Alzheimer's; CTE and Dementia; NIH Chief Talks Autism Electrical signals from neurons helped ...

Mitochondrial Complex I (NADH:ubiquinone oxidoreductase) is the largest enzyme complex of the respiratory chain, essential for cellular energy production. This multiprotein assembly couples the ...

Humanin represents a fascinating intersection of mitochondrial biology, cellular signaling, and organismal physiology. Its ...

Researchers have discovered how the metabolism of mitochondria supports T-cell proliferation and prevents exhaustion in ...

Danielle Alexander has always had eating and weight problems since the day she was born … but was only diagnosed with an exceptionally rare form of mitochondrial disease when she was 33.

The study revealed that deficiency in this system leads to increased mitochondrial oxidative stress. This was evidenced by increased hydrogen peroxide (H 2 O 2) release and a lower peroxiredoxin 1 ...

MT-ND5 encodes a critical subunit of mitochondrial complex I, essential for oxidative phosphorylation. De novo MT-ND5 mutations were introduced, and the full molecular etiology post-MT-ND5 ...

A three-person IVF technique has resulted in eight healthy children born without risk of inherited metabolic disease by transferring DNA to donor eggs, researchers announced.

Mitochondrial disorders can cause serious health problems, including paralysis, heart failure, brain damage, strokes and blindness. Children born with one of these disorders often live short ...