Changes in how brain cells generate energy may drive the development of Alzheimer's disease and influence how patients ...

Mitochondrial Complex I (NADH:ubiquinone oxidoreductase) is the largest enzyme complex of the respiratory chain, essential for cellular energy production. This multiprotein assembly couples the ...

E lectrical signals from neurons helped predict whether mild cognitive impairment would develop into Alzheimer's disease within 2.5 years. ( Imaging Neuroscience) Mitochondrial complex I deficiency ...

Researchers have discovered how the metabolism of mitochondria supports T-cell proliferation and prevents exhaustion in ...

Danielle Alexander has always had eating and weight problems since the day she was born … but was only diagnosed with an exceptionally rare form of mitochondrial disease when she was 33.

The study revealed that deficiency in this system leads to increased mitochondrial oxidative stress. This was evidenced by increased hydrogen peroxide (H 2 O 2) release and a lower peroxiredoxin 1 ...

A three-person IVF technique has resulted in eight healthy children born without risk of inherited metabolic disease by transferring DNA to donor eggs, researchers announced.

MT-ND5 encodes a critical subunit of mitochondrial complex I, essential for oxidative phosphorylation. De novo MT-ND5 mutations were introduced, and the full molecular etiology post-MT-ND5 ...

Mitochondrial disorders can cause serious health problems, including paralysis, heart failure, brain damage, strokes and blindness. Children born with one of these disorders often live short ...