Russell Brand reprises his role as Dr. Nefario, Gru's future partner in crime, in the Minions sequel, while the iconic Julie Andrews has also come back to voice the villain's mother Marlena once more.

Thankfully, Dr. Nefario develops an antitdote to PX-41, and no Purple Minions exist by the time Despicable Me 2 concludes.

The Minions get their own Despicable Me spin-off movie. ... Eventually, that quest brings us to the 1960s, and the promising Villain Con (which has Dr Nefarious hiding in the background, ...

Russell Brand (Young Dr. Nefario) Russell Brand has been around for some time in the business and he’s a great choice for voicing young Dr. Nefario, Gru’s partner, in Minions: The Rise of Gru.

A prequel to the Gru-starring adventures, Minions charts the yellow blobs' journey through history from single-celled organisms to jabbering henchmen by way of history's most nefarious baddies.