Multivariate analysis of expression of the microtubule-associated protein, tau, predicts improved progression free and overall survival in patients with metastatic HER-2-negative breast cancers ...

Using a novel quantitative chemoproteomic strategy, the team uncovered a protective role of dopamine (DA) in regulating the function of the microtubule-associated protein Tau.

Hyperphosphorylation of microtubule-associated protein tau is a major driver in the pathogenesis of a variety of neurodegenerative diseases, including Alzheimer’s disease (AD) and other tauopathies.

Background: Microtubule associated proteins (MAPs) endogenously regulate microtubule stability, have been reported as prognostic markers, and may predict response to taxane therapy. Previous work in ...

About BIIB080BIIB080 is an investigational antisense oligonucleotide (ASO) therapy designed to target microtubule-associated protein tau (MAPT) mRNA to reduce the production of tau protein ...

Biogen Inc. has reported promising data from a phase 1b trial of BIIB080, an investigational antisense oligonucleotide therapy that reduced soluble tau protein in cerebrospinal fluid in patients ...

A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, reveals that the protein Tau – a key ...

CAMSAP3 is a recently found microtubule-binding protein. It specifically binds to one of the two tips of each microtubule and stabilizes the tip to prevent it from depolymerizing." Tomohiro Shima ...

BIIB080 is an investigational antisense oligonucleotide (ASO) therapy designed to target microtubule-associated protein tau (MAPT) mRNA to reduce the production of tau protein. Abnormal ...