While Messi has played his magic mainly at Barca and now also Inter Miami, Ronaldo has done it across different divisions, i.e., England’s Premier League, Spain’s La Liga, and Italy’s Serie A.

If Ronaldo and Messi can play one more time, it would be a dream matchup for many soccer fans, even at the players' advanced sporting ages. Messi is no spring chicken himself, turning 38 on June 24.

Both Messi and Ronaldo's high-end cards remain some of the most hotly-chased in The Hobby. Over the last year, Card Ladder registers 177 Messi sales of $10,000 or more.