When a child takes a 1 milligram dose of melatonin, the hormone quickly enters their bloodstream, signaling to the brain that it’s time for sleep. Melatonin reaches levels in the blood that can be ...

Side effects associated ... Since most research on melatonin has focused on short-term effects, we don't know much about long-term use. One study did find that long-term use of melatonin is ...

One study found that melatonin is safe for adults for up to seven years, with few and mild side effects. Some studies raise concerns that long-term melatonin use may delay puberty in children and ...

But some research suggests melatonin supplements may also treat delayed sleep-wake phase disorder. This circadian rhythm disorder typically occurs in children. In addition, people with chronic ...