Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Researchers present novel therapeutics that rejuvenate a previously undruggable mitochondrial regulator of aging through a new mode of enzyme activation. Leveraging a newly identified biophysical ...

Scientists have identified the role an enzyme, crucial to the body’s metabolism, plays in the development of kidney disease, opening the door to new methods of prevention and treatment of this ...

It turns out that a gene called LTR5Hs activates a gene that affects the growth of an embryo and the proliferation of stem cells.

Living cells contain a world of complex parts, which are constantly in motion. Many functions of these parts are still not fully understood, but likely harbor answers to many of our questions about ...

VQ-101 is the first small molecule to demonstrate >70% activation of the lysosomal enzyme glucocerebrosidase (GCase ... at all doses tested. Based on human genetics and Vanqua’s preclinical studies in ...

Abdominal pain is a hallmark of many digestive disorders, including inflammatory bowel disease and irritable bowel syndrome.

Back in 2021, at the height of the pandemic, scientists at Pfizer revealed the development of a novel antiviral molecule, designed to hinder the SARS-CoV-2 virus’s ability to replicate. Clinical ...