In severe aortic valve regurgitation, Mayne’s sign is a decrease in the diastolic blood pressure of 15 mm Hg or greater in the arm when it is held above the head. The clinical significance of ...

Bridgewater-based Cosette Pharmaceuticals announced Feb. 20 it entered into an agreement to acquire Mayne Pharma Group Ltd. in a $430 million deal. Mayne is an Australian-headquartered specialty ...