Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

Caroline Cray was diagnosed with mast cell activation syndrome in May 2019 after repeated anaphylactic episodes Jordan Greene is Society and Culture writer-reporter at PEOPLE. She has been working ...

Mast cell mediators, histamine, tryptase and NGF, released upon activation can excite sensory nerves and promote their growth. Corticotropin-releasing hormone, sensory nerves and the number of ...