Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially ...

Barzolvolimab cut mast cells by -36 vs. -2.7 in placebo at 12 weeks. Despite cell depletion, no symptom or endoscopic improvement in eosinophilic esophagitis. Want to trade this news? Get access to ...

Scientists show that prenatal stress reshapes fetal mast cells and sensory neurons, creating a fragile skin barrier that sparks early-life eczema in mice. Study: Maternal stress triggers early-life ...