Galmed Pharmaceuticals Ltd (NASDAQ: GLMD) announced results showing significant effects of Aramchol in a preclinical lung and gastrointestinal (GI) fibrosis model. Treatment with Aramchol resulted ...

A unique feature of the paper, said Kaminski, is that it provides the first computational model ... the human lung," Kaminski said. Animal models for IPF work to show how pulmonary fibrosis ...

Similar to what has been observed in patients, the surviving mice went on to develop progressive fibrosis and loss of lung function. Using the new animal model, the researchers will next look at ...

Using a newly created pig model ... and lung disease in the pigs, which mimic CF in humans. It's been more than 20 years since scientists first discovered the gene that causes cystic fibrosis ...

SCIENCE PHOTO LIBRARY A RIKEN-developed mouse model of an enigmatic lung disease promises to unlock new biological insights and catalyze the development of treatments for millions affected globally 1.

Idiopathic pulmonary fibrosis is a potentially lethal disease ... starting with the development of an animal model that faithfully reproduces the human disease. The most widely used model until ...

Panel A shows a conceptual model of the pathobiology of idiopathic ... and VEGFR vascular endothelial growth factor receptor. Animal models of lung fibrosis do not recapitulate IPF.

At the basic level, we know the genetic cause of cystic fibrosis: it is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance ...

The lung is one of the tissues ... is the lack of experimental model systems that recapitulate how exactly the damage occurs in people. Small animal preclinical models fail to produce key ...

chronic lung disease and pulmonary fibrosis. And the researchers hope to adapt the model to be able to accurately assess more than ultrasounds, such as CT scans and X-rays.