Norepinephrine-producing neurons in the locus coeruleus, a small nucleus in the brainstem, have been discovered to have two distinct types of cells that connect linearly via gap junctions -- novel ...

New research shows that older adults may compensate for age-related cognitive decline by enhancing activity in a specific ...

A small nucleus in the brainstem called locus coeruleus (literally the “blue spot,”) is the primary source of a major neuromodulator, norepinephrine (NE), an important mediator of the ‘fight ...

The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep. Anyone with insomnia knows the impatience and ...

Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells. Nature Biotechnology , 2023; DOI: 10.1038/s41587-023-01977-4 Cite This Page : ...

More information: Yunlong Tao et al, Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells, Nature Biotechnology (2023). DOI: 10.1038/s41587-023-01977-4.

Small and seemingly specialized, the brain's locus coeruleus (LC) region has been stereotyped for its outsized export of the arousal-stimulating neuromodulator norepinephrine. In a new paper and ...

Norepinephrine neurons in the locus coeruleus regulate heartbeat, blood pressure, arousal, memory, attention and “fight or flight” reactions. Humans have approximately 50,000 LC-NE neurons in ...

Scientists have inferred that the locus coeruleus must play a nuanced role. "If your toddler runs out into the street, you want your motor system tuned up so you can chase after them," Luskin said.

Norepinephrine (INN) (abbreviated norepi or NE) is the US name for noradrenaline (BAN) (abbreviated NA or NAd), a catecholamine with multiple roles including as a hormone and a neurotransmitter.