Glycolysis, Pyruvate Oxidation and the Krebs Cycle Glycolysis, the process of splitting a six-carbon glucose molecule into two three-carbon pyruvate molecules, is linked to the Krebs cycle.

The citric acid cycle is also known as the Krebs cycle or the tricarboxylic acid ... cycle begins with the reaction that combines the two-carbon acetyl CoA with a four-carbon oxaloacetic acid ...

He adds that when run in reverse, the Krebs cycle “could have been responsible for building organic molecules from carbon dioxide ... for making isotopically labeled metabolites for medical ...