Transposable elements, or "jumping genes", were first identified by Barbara McClintock more than 50 years ago. Why are transposons so common in eukaryotes, and exactly what do they do? In addition ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Surprisingly, it wasn’t some mutation that knocked out this gene but rather a so-called “jumping gene” known as AluY. Jumping ...

For decades, scientists dismissed transposable elements, also known as transposons or “jumping genes”, as useless “junk DNA”. But are they really? The early speculations of both McClintock ...

But Chiappinelli, then a postdoctoral fellow in Stephen Baylin’s lab at Johns Hopkins University, also saw an upregulation in genes involved in innate immunity ... these elements are mere relics of ...

No one believed Barbara McClintock in 1951 when she first described DNA that "jumped" from site to site within maize chromosomes, altering the expression of genes near the sites of integration. In due ...

3-D modeling shows that Alu insertions within the TOMM40 gene could make the channel protein it encodes fold into the wrong shape, causing the mitochondria's import machinery to clog and stop working.

UMD researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines.

The research team also discovered a gene called sdg-1 that helps regulate 'jumping genes' -- DNA sequences that tend to move or copy themselves to different locations on a chromosome. While ...