Novel Protein Is Both Ion Channel And Enzyme Date: January 19, 2001 Source: Howard Hughes Medical Institute Summary: Researchers have discovered a new protein component of cell-signaling pathways ...

A new study shows that loss or chemical inhibition of a protein, known as acid sensing ion channel protein, reduces innate fear behavior in lab animals, making normally timid mice relatively fearless.

becomes a five-protein "pentamer." The researchers found strong evidence that this structural rearrangement underlies a hitherto unexplained ion-channel phenomenon called pore dilation.

We have now discovered the gene encoding the protein that forms the ASOR channel," explains Professor Thomas Jentsch, head of the research group on Physiology and Pathology of Ion Transport at the ...

By deleting the ORAI2 protein from the CRAC channel, the scientists showed that the flow of calcium ions into cells was markedly increased. Furthermore, they found the deletion of both proteins ...

The researchers found that mice without the ion channel protein TRPA1 showed fewer signs of asthma. "When compared to normal mice, those lacking the gene for TRPA1 had greatly diminished ...

“What we have found is that in order to achieve their high temperature sensitivity, the ion channel needs to undergo extreme structural changes in their functional state, and these extreme changes ...

This is the first discovery of a mechanical itch protein, and stems from earlier work concerning an ion channel protein PIEZO1 in the outer membrane of cells, which opens up in response to ...

IOWA CITY, Iowa, Aug. 2 (UPI) -- A U.S. study shows inhibiting an acid sensing ion channel protein can reduce fearful behavior, making normally timid lab mice relatively fearless. University of ...

A University of Iowa study shows that loss or chemical inhibition of a protein, known as acid sensing ion channel protein (ASIC1a), reduces innate fear behavior in lab animals, making normally ...