These factors form two cascades known as the intrinsic and extrinsic coagulation pathways. Both of these pathways lead to the formation of thrombin. The extrinsic pathway also facilitates the ...

Factor IXa then moves into the intrinsic pathway and combines with ... Thus, the end product of both the extrinsic and intrinsic coagulation systems is thrombin. Since thrombin is the central ...

Extrinsic tenase complexes are protein complexes that consist of two coagulation factors (tissue factor TF and factor VIIa) and initiate the activation of the coagulation cascade when they come ...