Illinois State Police said two people died in a three-vehicle crash after a semi-trailer traveling north on Interstate 55 crossed the median and wound up in the wrong direction in the southbound ...

A North Carolina woman was killed and two people sustained life-threatening injuries in a multi-vehicle collision on southbound Interstate 55 near the Chatham exit just past 7:30 p.m. Tuesday.

ST. LOUIS — All southbound lanes of Interstate 55 at South Broadway have reopened after an incident Thursday morning. According to the St. Louis Metropolitan Police Department, the incident ...

Cancel anytime. JEFFERSON COUNTY — A 49-year-old man from Perryville, Missouri, died when his truck struck the rear of another truck Monday morning on Interstate 55 south of Festus. The ...

An immense cleanup effort was underway along Interstate 55 in south-central Illinois late Monday night, hours after a dust storm caused a series of collisions, killing at least six people and ...

MDOT Spokesperson Michael Flood said temporary road closures at the entrance ramp from Pearl Street to Interstate 55 South began Friday, Oct. 18, and will conclude Friday, Nov. 15. Flood said the ...

Illinois State Police responded to the area of Interstate 55 south of South Damen Avenue at around 1:55 a.m. Police believe a motorcycle stopped in the middle lane and the driver got off of it.

The Missouri Department of Transportation has announced that it plans to open a new roundabout under construction in the southeast portion of the Interstate 55/Highway 67 interchange south of ...

ST. JOHN THE BAPTIST PARISH, La. (WGNO) — A crash involving multiple commercial vehicles has shut down parts of Interstate 55 south in St. John the Baptist Parish Friday morning, Feb. 7.