Summary Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include ...

Insulin resistance is a hallmark of multiple metabolic disorders, including type 2 diabetes, obesity, metabolic syndrome, and polycystic ovary syndrome. It ...

Eli Lilly and Company announced new data regarding the mechanism of action of basal insulin peglispro (BIL). When BIL and insulin glargine were each administered to achieve complete suppression of ...

After discovering that differentiated podocytes were insulin responsive in vitro, we explored the underlying mechanism responsible for this action. The glucose transporter that is classically ...

Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2.

A newly discovered mechanism that leads to liver dysfunction may be a key factor in type 2 diabetes and other metabolic disorders in individuals with obesity, according to a new study led by ...

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity. The insulin superfamily of ...