JMU scientists studied insulin-producing cells in fruit flies, finding that secretion is influenced by gut hormones, ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

The discovery of the nuclear receptor PPAR-γ as the molecular target of TZDs suggested a mechanism for their beneficial effects on insulin action. As PPAR-γ is mainly expressed in fat cells ...

Without this feedback mechanism, as occurs in the uncontrolled ... to the hyperinsulinemia necessary to match the defect in insulin action. In this regard, it seems more than coincidental that ...

Research has shed light on the intricate mechanisms of insulin production in fruit flies, revealing surprising parallels with ...

Bromocriptine has not been shown to augment insulin secretion or enhance insulin ... This centrally acting antidiabetic agent has a novel mechanism of action; reduces plasma glucose, triglyceride ...

Exercise has long been believed to improve cognition, but the mechanisms involved have been unclear ... "Our work suggests that therapies that target brain insulin action may be able to ward off ...

Insulin allows cells to absorb and use glucose. In people with insulin resistance, the cells are unable to use insulin effectively. Insulin resistance occurs when cells in the body do not respond ...