IgG4-related disease is a multifaceted, systemic fibroinflammatory condition that can affect virtually any organ, with autoimmune pancreatitis representing one of its most well‐characterised ...

Even pancreatitis, one of the most concerning manifestations of IgG4-related disease is very subclinical. Patients have relatively few symptoms, and this is very much counter to what we understand ...

Autoimmune pancreatitis (AIP) is a clinical condition characterized by inflammation of the pancreas, caused by the body's hypersensitivity to its own proteins. AIP is typically accompanied by other ...

Autoimmune pancreatitis (AIP), a systemic autoimmune disorder, ... called IgG4-related disease (IgG4-RD). When induced repeatedly with polyinosinic-polycytidylic acid ...

Recent results from a cross-sectional study show that patients with immunoglobulin G4-related autoimmune pancreatitis (AIP) experience a high burden of disease-associated damage, iatrogenic injury ...

An imbalance in specific antibodies can be a sign of autoimmune disease. High levels of IgG4, a particular type of antibody, can lead to widespread organ damage and mass growth.

So, autoimmune pancreatitis, which has gone by a number of different names for the past several decades, is, in fact, one of the most important manifestations of IgG4-related disease. So, IgG4 ...

Advances Amgen's Leadership in CD19 Directed, B-Cell Depletion Therapies for Serious Autoimmune Diseases Including NMOSD, IgG4-RD and gMG IgG4-RD can occur in multiple organs and lead to fibrosis ...

The FDA had previously granted a breakthrough therapy designation to Uplizna for the treatment of IgG4-RD. Year to date, shares of Amgen have rallied 18.9% compared with the industry’s rise of 1.2%.

Beamon set out on a journey, and 26 doctors, 37 procedures and more than 17 years later, a rheumatologist finally cracked the confounding code: She had immune disorder IgG4-related disease, and ...