IgG4-related disease is a multifaceted, systemic fibroinflammatory condition that can affect virtually any organ, with autoimmune pancreatitis representing one of its most well‐characterised ...

But the pancreatitis associated with IgG4-related disease is often subclinical. And so, for many months or years, the pancreatitis can be destroying the pancreas.

Autoimmune pancreatitis (AIP) is a clinical condition characterized by inflammation of the pancreas, caused by the body's hypersensitivity to its own proteins. AIP is typically accompanied by other ...

Recent results from a cross-sectional study show that patients with immunoglobulin G4-related autoimmune pancreatitis (AIP) experience a high burden of disease-associated damage, iatrogenic injury ...

Autoimmune pancreatitis (AIP) is an inflammatory disease of the pancreas and has been previously characterized to involve multiple inflammatory cells and molecules. However, the crucial molecules ...

IgG4-related sclerosing disease is a condition that may affect a single organ or multiple organs at once, causing lumps, swellings, and masses to form and leading to widespread inflammation.

Nika Beamon set out on a journey, and 26 doctors, 37 procedures and more than 17 years later, a rheumatologist finally cracked the code.

So, autoimmune pancreatitis, which has gone by a number of different names for the past several decades, is, in fact, one of the most important manifestations of IgG4-related disease.

Amgen AMGN announced that the FDA has approved its rare disease drug Uplizna (inebilizumab) for a new indication. The regulatory body has now approved Uplizna for the treatment of adults living ...

"The clinical community now has an FDA-approved therapeutic innovation for patients that targets underlying disease mechanisms and helps to control disease activity by reducing flares in IgG4-RD.

According to Dr Medhavy, although both patients with the TNIP1 mutation had slightly different forms of autoimmune disease, they both had abnormally high levels of IgG4 antibodies in their blood.