The drug is a fusion protein comprising the human interleukin (IL)-1 type 1 receptor (extracellular domain and accessory protein) and the Fc portion of human IgG1. Regeneron's drug is the only ...

Experimental models of gouty inflammation have shown that neutrophil influx in response to MSU crystals is reduced in mice deficient in inflammasome components or in the IL-1 receptor (IL1-R1 ...

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states.