One important question is whether and how IL-17 signaling is negatively regulated to adequately prevent inflammatory disorders. It has recently been shown that blockade of the PI3K pathway led to ...

For IL-17, the unique positive and negative feedback regulatory mechanisms of the signaling pathway render it a moderate signaling activator compared to other inflammatory stimuli.” Future drugs ...

IL-17 mediated signaling is known to induce the expression of cytokines and other effectors that can cause a variety of immunological diseases such as psoriasis and Chronic Obstructive Pulmonary ...

IL-17 mediated signaling is known to induce the expression of cytokines and other effectors that can cause a variety of immunological diseases such as psoriasis and Chronic Obstructive Pulmonary ...