SaveHealth reports that high cholesterol affects 1 in 3 Americans, often without symptoms until serious events occur. It is ...

Given the high risk of genetic familial hypercholesterolemia for early cardiovascular disease and premature mortality, National Heart, Lung, and Blood Institute (NHLBI) guidelines recommend ...

Follow along on our guide to Hypercholesterolemia -- i.e., high cholesterol -- which can increase the risk of heart disease, stroke, and other cardiovascular problems. An estimated 40% of adults ...

Most guidance for management of hypercholesterolemia apply across patient demographics and characteristics. However, there are some special considerations for specific groups.

DEAR DR. ROACH: I am a 69-year-old woman who was diagnosed with familial hypercholesterolemia (FH). I used statins for over a decade but developed vulvar lichen sclerosus (LS), which only went ...

This approach, known as cascade screening, has the particular advantage over universal screening of identifying more severe subtypes of familial hypercholesterolemia. This is because people whose ...

Figure 1. Altered lipid metabolism in homozygous familial hypercholesterolemia and points of drug action. Points of drug action: (A) LDL receptor-mediated endocytosis: statins and PCSK9 inhibitors.