The Hedgehog (Hh) signalling pathway plays many important roles in development, homeostasis and tumorigenesis. The critical function of Hh signalling in bone formation has been identified in the ...

or after cancer-related bone resections,” said the study's co-author Jay Lieberman, M.D., chair and professor of orthopedic surgery at the Keck School of Medicine of USC. The hedgehog (HH ...

Hedgehog Protein Blocks Fat Production, Produces More Bone. ScienceDaily . Retrieved May 24, 2025 from www.sciencedaily.com / releases / 2006 / 01 / 060111073720.htm ...

"In mammals, it appears that hedgehog signaling regulates adult stem cells, diverting them from forming fat cells and redirecting them to become bone," Dr. Graff said. "Unfortunately, as humans age ...