The microbial community in the human gut plays a central role in various diseases. An important form of chemical ...

Now, scientists led by Trisha Pasricha, Beth Israel Deaconess Medical Center, Boston, report that damage to the upper gastrointestinal mucosa almost doubles a person’s risk of developing Parkinson’s ...

Metabolites from gut bacteria can regulate the immune system and influence human behavior, but how many of these molecules ...

Well, the GI mucosa is part of the mucous membrane. It’s the part found in the stomach and protects the stomach wall from acid and digestive enzymes. A break in the mucosal lining of the stomach ...

While the exact mechanisms involved in this communication are not fully known, multiple alterations in the gut microbiome have been reported with neurodegenerative diseases such as Parkinson’s ...

In 1985, rheumatologist Michael Smith showed that patients with ankylosing spondylitis have a significantly increased permeability of the intestinal mucosa. 1 Similar “leak” evidence was found in the ...

Western diets that are high in sugars, fats, and processed foods have been linked to a wide variety of health ailments. Now, researchers have determined that Western diets can also disrupt the crucial ...

The gut barrier is made up of the mucus layer, gut microbiome, epithelial cells, and immune cells in the lamina propria. When this apparatus is disrupted by factors such as infection, low-fiber ...

The diagnosis of type 1 diabetes was based on World Health Organization criteria, [19] and all the patients were on insulin treatment. Sixteen also had celiac disease, 10 thyroidal autoimmune ...

GLP-2: origin and function GLP-2 is a 33-amino acid peptide primarily produced in the intestines by L-cells (gut cells that release hormones to regulate digestion and appetite) and is also ...

Researchers uncovered how estrogen heightens gut sensitivity in females by activating PYY-secreting L-cells, which stimulate serotonin release from EC cells. This paracrine circuit intensifies ...