To understand how DJ-1 hydrolyzes cyclic 3-phosphoglyceric anhydride—a highly reactive, toxic cellular metabolite—researchers ...

Our body is made up of millions of cells that coordinate daily function. They are constantly working to maintain activity and ...

A mutant DJ-1 gene causes recessive Parkinson's disease, but the molecular mechanism of this process has not been well ...

Letter Published: 01 April 1950 Mechanism of Glyceraldehyde Inhibition of Glycolysis D. M. NEEDHAM, L. SIMINOVITCH & S. M. RAPKINE Nature 165, 521 (1950) Cite this article ...

More information: Haihua Zhang et al, ING5 inhibits aerobic glycolysis of lung cancer cells by promoting TIE1-mediated phosphorylation of pyruvate dehydrogenase kinase 1 at Y163, Frontiers of ...

A novel mechanism for overexpression of c-Myc, a proto-oncogene in cancer cells The deubiquitinating enzyme USP17 regulates c-Myc levels and controls cell proliferation and glycolysis ...