Researchers have discovered how the C. diff toxin B recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections.

Included patient encounters had a positive C difficile PCR test and either a toxin EIA-positive assay (confirmed cases) or toxin EIA-negative assay (controls). Available encounter stool specimens ...

Patients who were missing components for recurrent C. difficile infection criteria (for example, having a positive toxin test result) were also counted as reinfected. Limitations included that the ...