Researchers have revealed the mechanism underlying GPCR function using a GPS nuclear magnetic resonance (NMR) technique.

Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative anti-inflammatory and ...

Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes ...

Researchers have captured a time-resolved video of a protein interaction essential to healthy brain development.

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches ...

Nine (27%) patients had prior anti-BCMA CAR T-cell therapy. Fig 1. Flow diagram. BCMA, B-cell maturation antigen; CAR, chimeric antigen receptor; GPRC5D, G protein–coupled receptor, class C group 5 ...

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...

Septerna, Inc. (Nasdaq: SEPN), a biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that Jeffrey Finer, M.D., Ph.D., Chief Executive ...

Dublin, May 06, 2025 (GLOBE NEWSWIRE) -- The "G-Protein Coupled Receptor (GPCR) Targeting: Technologies and Global Markets" report has been added to ResearchAndMarkets.com's offering. The global G ...

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

Talquetamab is a T-cell–redirecting bispecific antibody targeting G protein–coupled receptor class C group 5 member D (GPRC5D). 13-15 In the MonumenTAL-1 study, more than 71% of the patients ...

From September 1, 2021, to March 23, 2022, 33 patients were infused with anti-GPRC5D CAR T cells. At a median follow-up of 5.2 months (range, 3.2‐8.9), the overall response rate was 91% (95% CI, 76 to ...