The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...

Researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior. Mount Sinai researchers have ...

Regulatory T cells, which prevent the immune system from attacking the body, were the subject of this year’s Physiology or ...

Opioids slot into opioid receptors and activate them. This sends signals to your brain to relieve pain and promote pleasure. Both endogenous opioids, which your body naturally produces, and exogenous ...

An essential component of the lymphatic system, the thymus, a pyramid-shaped organ located in the thoracic cavity, is responsible for producing T-cells. For centuries, the thymus was believed to be an ...

A Monash University study of almost 400,000 people, published in the journal Cardiovascular Research, is the first to indicate, in humans, that the signaling of substances called short-chain fatty ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...