Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

Transcription factors are proteins that bind to specific DNA sequences to control gene expression, guiding cells to become specific types—such as skin, muscle, or placenta cells. While TFs are ...

Studying the expression of these transcription factors in patients with colorectal cancers could reveal biomarkers to help determine overall survival in people with a subgroup of colorectal ...

Transcription factors are critical proteins that regulate gene expression, playing a pivotal role in controlling key processes such as lipid metabolism, inflammation, apoptosis, and fibrosis in MAFLD.

For years, scientists have considered transcription factors to be undruggable, but new research published this month in Molecular Cell shows they may be druggable after all (2024, DOI: 10.1016/j ...

Talus Bio tacks on $11M to target hard-to-reach transcription factors By Gabrielle Masson Aug 20, 2024 11:05am Oncology biotech venture capital venture capital (VC) Genome ...

Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal ...

Roche teams up with transcription factor trailblazer Flare in new $1.8B-plus cancer pact By Gabrielle Masson Nov 12, 2024 7:00am Roche Flare Therapeutics Oncology small molecules ...

A new study led by Prof. Yosef Buganim from the Hebrew University of Jerusalem and Dr. Abdenour Soufi from the University of Edinburgh reveals how transcription factors (TFs)—key proteins that ...