Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disease affecting the frontal and temporal lobes that regulate higher cognitive brain functions such as personality, behavior ...

One previous study showed that a cohort of 68 patients with FTD worsened by an average of 3.57 points over a 12-month period per the Clinical Dementia Rating - Frontotemporal Lobar Degeneration ...

Canada The three main types of frontotemporal lobar degeneration (FTLD) are characterized by the accumulation of abnormal proteins, namely tau, TDP-43 and FUS. The distribution of these proteins ...

Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids – also know ...

Alterations in GRAMD1B levels affect cholesterol balance, lipid stores, and tau modification, all linked to neurodegenerative diseases like frontotemporal lobar degeneration (FTLD) and Alzheimer's.

About 50,000 to 60,000 Americans live with FTLD. Alzheimer's disease is the most common cause of dementia. An estimated 6.9 million Americans who are age 65 and older are living with Alzheimer's ...

Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51 , 1546–1554 (1998). Article CAS Google Scholar ...

Neumann et al. have identified the ubiquitinated protein that forms inclusion bodies in neurons of both individuals with frontotemporal lobar degeneration (FTLD) and those with amyotrophic lateral ...