Pfizer said its experimental gene therapy for a rare genetic blood-clotting disorder succeeded in a large ... a lack of blood-clotting protein called factor VIII. Without enough of that protein ...

such as a mutation – a change in the gene's instructions – the body may make a clotting factor incorrectly or not make it at all. You can also have what's called an acquired bleeding disorder ...

If you have factor XI deficiency, your blood doesn’t clot properly because it lacks specific proteins called “clotting factors.” It causes a mild form of hemophilia and may increase bleeding.

The U.S. Food and Drug Administration approved French drugmaker Sanofi's hemophilia therapy, introducing a new type of ...

Factor V Leiden is an incurable, genetic blood clotting disorder. It can cause complications such as blood clots in the legs, lungs, and other parts of the body. Exercising and eating a healthy ...

A new concentrate of clotting factors ... up to 80 units (1.5 to 2.0 ml) per kilogram of body weight there appeared to be a mean rise of approximately 1 per cent of factor IX activity in plasma ...

BENGALURU: When a five-year-old was hit by a three-wheeler while crossing the road in Bidar on Sept 2, it left ... the absence of Factor VIII, a critical component for blood clotting, made the ...

paving the way for a new type of treatment for patients with the rare blood clotting disorder, the regulator said on Friday. Sanofi’s subcutaneous, or under-the-skin, therapy helps prevent ...

demonstrates that administering non-activated four-factor prothrombin complex concentrate (4F-PCC) – a shelf-stable medication containing freeze-dried clotting factors – significantly reduced ...

The adeno-associated virus (AAV) vector-based therapy is given as a one-shot intravenous infusion, delivering a gene for Factor IX, a clotting factor ... is well above the $2.9 million that ...

Many people don't think much about whether their blood is clotting properly. However, when you have a bleeding disorder, a ...