Altered function of selectin glycoprotein adhesion molecules may modulate severity and organ-specific manifestations of autoimmune and inflammatory disease via changes in leukocyte trafficking ...

In all evaluable patients, the SLE Response Index (SRI)-4 response rates at week 12 were 50.0% (7/14), 61.5% (8/13) and 64.3% (9/14) in patients treated with orelabrutinib at 50mg, 80mg and 100mg ...

Systemic lupus erythematosus (SLE) is the most common type of lupus, a chronic autoimmune disease. Symptoms include fatigue, joint pain, and rashes across your nose and cheeks. While there’s no ...

Patient 4 with SLE, who had a rebound of proteinuria 4 months after CAR T-cell therapy and in whom follow-up renal biopsy did not reveal any histopathological signs of lupus nephritis (but ...

ADI-001 was granted Fast Track Designation by the FDA for the treatment of relapsed/refractory class III or class IV lupus nephritis (LN), and SLE with extrarenal involvement.

Systemic lupus erythematosus (SLE) is the most common form of lupus — it’s the type that 7 in 10 people with lupus have. It's what most people mean when they say "lupus." What causes SLE? Experts ...