Our previous study demonstrated that distant estrogen response elements (DEREs) located on chromosome 20q13 are frequently amplified and translocated to other chromosomes in ERα-positive breast ...

which then bind as dimers to estrogen-response elements in the regulatory regions of estrogen-responsive genes and associate with basal transcription factors, coactivators, and corepressors to ...

and this ligand–receptor complex binds to and activates specific sequences in the regulatory region of genes responsive to estrogen, known as estrogen-response elements. These genes in turn ...

Premenopausal women with stage cT2 to 4b, any N, M0; estrogen receptor and progesterone receptor ... in premenopausal patients treated with letrozole as NET for endocrine-responsive breast cancer, ...