Subsequently, nine peptide sequences (SP 1 to 9) were extracted, and their effects on human estrogen receptor alpha (ERα)-mediated transcriptional activation were assessed.

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

About H3B-6545 Estrogen receptor alpha (ERα) plays an important oncogenic role in the genesis and progression of luminal breast cancers,1 and historically has been a target of endocrine therapies.

Cherubini, A., Ostadreza, M., Jamialahmadi, O. et al. Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women.

Abstract 529 Background: Neoadjuvant chemotherapy (NAC) is commonly administered to patients (pts) with estrogen receptor alpha (ER) negative (immunohistochemistry [IHC] 0%) and ER-low (IHC 1-10%) ...

The researchers propose that interacting with the ER-alpha-Clic1 complex enables estrogen to trigger fast neuronal responses through Clic1 ion currents. The study appeared in Science Advances.

An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Science Advances, 2022; 8 (3) DOI: 10.1126/sciadv.abk0185 ...

Estrogen can be linked to a higher risk of hormone-sensitive cancers, such as breast, endometrial, ovarian, and cervical cancers. Flaxseeds are a concentrated source of dietary fiber.