Researchers at LMU and Stanford University reveal how cells regenerate protein factories at endoplasmic reticulum. The synthesis of proteins in the cell is a key process of life.

Today, scientists know that the endomembrane system includes the endoplasmic reticulum (ER), Golgi apparatus, and lysosomes. Vesicles also allow the exchange of membrane components with a cell's ...

Endoplasmic reticulum stress plays a crucial role in several pathophysiological events such as neurodegenerative diseases, tumorigenesis, fatty liver, cardiovascular disease, diabetes, antigen ...

We found that endoplasmic reticulum stress markers, activating transcription factor 6, inositol-requiring enzyme 1a, protein kinase RNA-like endoplasmic reticulum kinase, C/EBP homologous protein, and ...

NAC acts as a gatekeeper, granting SRP access to nascent proteins destined for the endoplasmic reticulum. (Elke Deuerling) NAC ensures that only proteins destined for the ER are passed on to the SRP.

DJ-1 is critical for the integrity and function of endoplasmic reticulum-mitochondria tethering Yi Liu *, Sirui Jiang, Xiaopin Ma, Sandra L. Siedlak, Sandy Torres, Shengdi Chen, Xiongwei Zhu * ...

Massimiliano Corso, Fabrizio G. Doccula, J. Romário F. de Melo, Alex Costa, Nathalie Verbruggen, Endoplasmic reticulum-localized CCX2 is required for osmotolerance by regulating ER and cytosolic Ca2+ ...