Mast cell activation syndrome, a disorder involving immune cells gone awry, is increasingly recognized as the culprit behind many medical mysteries. The first key to understanding this complex ...

Cellular nutrients come in many forms, including sugars and fats. In order to provide a cell with energy, these molecules have to pass across the cell membrane, which functions as a barrier ...

Subsequent cryo-EM imaging of the complexes that had survived the preparation process revealed insights into the T-cell receptor activation mechanism. Tampé stated: “On the basis of our structural ...

Jasper is a clinical-stage biotechnology company focused on developing briquilimab as a therapeutic for chronic mast cell diseases. Briquilimab is a targeted aglycosylated monoclonal antibody that ...