cell–cell adhesion, signalling and ECM remodelling, combine to produce one concerted outcome — multicellular migration. With the advent of live-cell microscopy, many multicellular tissues have ...
Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...
Cell migration affects all morphogenetic processes and contributes to numerous diseases, including cancer and cardiovascular disease. Cell migration begins with protrusion of the cell membrane ...
Focal adhesions (FAs) are structures that connect cells to the extracellular matrix (ECM) (the cell's external ... through the promotion of focal adhesion maturation. This gene was pinpointed ...
Hosted on MSN10mon
Extracellular cell matrix stiffness may induce drug resistance of breast cancer cellsExtracellular cell matrix (ECM) plays a significant role in remodeling ... further modulating focal adhesion constituents and redistribution. Without EGF, EGFR activation of rigidity sensing ...
Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...
This study aims to characterise ECM components of the stem cell niche in ... by low-density plating and differential adhesion to plastic and fibronectin substrates. Cells were analysed by flow ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback