Spider-Man has some of the greatest villains in comic book history, which is why it's so strange that Marvel has moved away from one of them.

It's been over a decade since Doc Ock stole Peter Parker's body ... he resolves to be not just a hero, but a superior Spider-Man. But for many fans, the storyline that came after was anything ...

A Marvel Rivals fan created a Doctor Octopus Vanguard concept for the hero shooter, showcasing unique abilities. The community wants Doc Ock added to the game with the possibility of The Sinister ...

In Sony's first official poster for Spider-Man: No Way Home, some of the web slinger's most iconic villains return, including Alfred Molina reprising his role as Doc Ock from 2004's Spider-Man 2 ...