BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines ...

Clinical effectiveness of immune therapies of solid tumors requires a ... Identify the key roles of dendritic cells in cancer immunotherapy, including their use as antigen-loaded vaccines and ...

converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them. Glioblastoma is the most common brain cancer in adults and also the ...

Proteogenomic analysis identified IFNγ as a driver of conventional dendritic cell ... may be possible to activate immune cells that can track down and eliminate cancer cells hiding in hard ...

the dendritic cells also may train the rest of the immune system, including T cells, to recognize and attack tumor cells that express these same proteins. With the T cells on high alert to destroy ...

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint ... responsible for killing tumor cells. There are also generals, such as dendritic cells, that give out ...

The personalized immunotherapy works by activating the body’s natural immune response to target and eliminate cancer cells ... using autologous dendritic cells loaded with pancreatic ...

A newly identified rare cell subset that drives immune tolerance in dietary and gut microbiota may offer a new therapeutic ...

Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue ...

Different cells of this response include eosinophils, basophils, neutrophils, natural killer cells, macrophages, dendritic cells, and others. Once a pathogen is detected the innate immune system ...

Immune cells play fundamental roles in the development, progression, and resolution of both chronic inflammatory diseases and various cancer types. In ...