During circular DNA replication, the excised primer is readily replaced by nucleotides, leaving no gap in the newly synthesized DNA. In contrast, in linear DNA replication, there is always a small ...

In this type of pairing, adenine (A) forms two hydrogen bonds with thymine (T) in DNA or uracil (U) in RNA, while guanine (G) forms three hydrogen bonds with cytosine (C). These base pairs are highly ...

RNA is often compared to a copy from a reference book, or a template, because it carries the same information as its DNA template but is not used for long-term storage. Each ribonucleotide base ...

While scientists have long known the importance of helicase in DNA replication, "they did not know how DNA, helicases and ATP work together in a coordinated cycle to drive DNA unwinding," De ...

During DNA replication, the complementary base pairing ensures faithful copying of the genetic material. In RNA, cytosine also pairs with guanine. However, RNA is typically single-stranded and serves ...

Additionally, the scientists unexpectedly captured for the first time a detailed picture of how the "engine" driving the ...