Now researchers show that the loss of DNA methylation across the genome changes the timing of DNA replication and alters the shape of the 3-D compartmentalization of DNA, which helps steer gene ...
In their previous articles, "The mechanism of aging: Primary role of transposable elements in genome disintegration ...
Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...
Genome-wide methylation profiling is available at our genomics facility ... For the analysis we need good quality DNA in a concentration of 50 ng/ul in a minimum volume of 20-30 ul. Illumina ...
Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...
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