A base pair is a fundamental unit of double-stranded nucleic acids, such as DNA and RNA. It consists of two complementary nucleobases bound to each other by hydrogen bonds. The base pairing rules ...

In 2014, Romesberg successfully coaxed a cell to incorporate his custom X and Y base pair to its DNA, and found that it would remain there as long as he kept supplying the nucleotides. He’s now shown, ...

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A T to a G C. The new ...

Hoogsteen base pairing: An alternative configuration to Watson–Crick pairing in DNA, involving a 180° rotation of the purine base that results in unique hydrogen bonding and structural orientation.

(Nanowerk News) Synthorx Inc. announced today the official launch of the company, which will be focused on using synthetic biology to improve the discovery and development of new medicines, ...

William B. Melchior, Peter H. Von Hippel, Alteration of the Relative Stability of dA · dT and dG · dC Base Pairs in DNA, Proceedings of the National Academy of Sciences of the United States of America ...