For patients without and with PE, the median D-dimer values were 1.0 and 6.1 µg/mL, respectively; D-dimer values ranged from 0.2 to 128 µg/mL and from 0.5 to more than 10,000 µg/mL, respectively.

Preliminary scientific report. Lin, K., Xu, K., Daoust, R., et al. (2022) Diagnostic accuracy of age-adjusted D-dimer for pulmonary embolism among Emergency Department patients with suspected SARS ...

"Our analyses show that pulmonary embolism is ruled out by a D-dimer level of less than 1,000 ng/mL in patients with a low probability, and by a D-dimer level of less than 500 ng/mL in patients ...

A pulmonary embolism (PE) diagnostic strategy using a higher D-dimer threshold under the so-called YEARS rule combined with age adjustment for selected patients who couldn't be ruled out by PE ...

Bannelier, H., et al. (2024). Failure rate of D‐dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies.

Of 674 patients without a high probability of pulmonary embolism, 232 (34%) had a negative D-dimer assay and an uneventful follow-up, and 109 patients had CT evidence of pulmonary embolism. Of 318 ...

If the D-dimer level is ≥ 1000 ng/mL, CTPA is ordered. For those with one or more items on the modified YEARS protocol, pulmonary embolism can be excluded if the D-dimer test shows a level less than ...

For patients with suspected pulmonary embolism, diagnostic strategies to rule out PE that apply adapted D-dimer thresholds were safe and efficient, even in high-risk patients.Researchers reported ...

A negative D-dimer test (one that rules out pulmonary embolism) can help patients avoid more expensive, invasive diagnostic tests, like a computed tomography pulmonary angiogram, or CTPA.

Combining the Wells rule and a POC yielded a sensitivity and specificity of 94.5% and 51.0%, respectively, which when combined with a quantitative test changed to 98.6% and 47.2%, respectively.

Plasma D-dimer testing and computed tomography are overused in patients suspected of having a pulmonary embolism, according to new clinical guidelines from the American College of Physicians.

An international systematic review and individual-patient data meta-analysis (IPDMA) from over 20,000 patients with suspected pulmonary embolism (PE) shows that diagnostic strategies for ruling ...